The Diagram Shown Here Is Part of an RNA Transcript

question 17

Multiple Choice

The diagram shown here is part of an RNA transcript containing four open reading frames (M, H, K, and L) and three introns (1, 2, 3) . The sites labeled d1-d3 are nucleotides immediately before each intron on the 5' side and those labeled a1-a3 are nucleotides immediately after each intron on the 3' side. Splicing out an intron involves a spliceosome facilitating the cleavage of the DNA at the d and a sites at either end of the intron. A missense mutation takes place in open reading frame H. In which possible alternative splice forms of the transcript would the missense mutation not affect the polypeptide product?

• A)d1-a1 + d2-a2 + d3-a3
• B)d1-a2 + d3-a3
• C)d1-a1 + d2-a3
• D)d1-a3
• E)None of the answer options is correct.

---

Definitions:

Net Income

Represents the earnings of a company after subtracting all costs and expenses from total revenue, indicating the company's financial health.

Accrued Liabilities

Expenses that have been incurred but have not been paid at the end of the accounting period.

Indirect Method

A accounting technique used to prepare the cash flow statement, converting net income into net cash flow from operating activities by adjusting for non-cash items and changes in working capital.

Net Income

Total earnings of a company after all expenses and taxes have been deducted from total revenue.