A Mutation Is Found That Prevents Transcription of the HOX3A

question 160

Multiple Choice

A mutation is found that prevents transcription of the HOX3A gene, which is known to be in chromosome 12. Genetic mapping of the mutation suggests that it is located in chromosome 11. Which of the following could make these two observations possible?

• A)The mutation affects a transcription factor that binds to HOX3A gene sequences.
• B)The mutation changes the DNA sequence of an enhancer of the HOX3A gene.
• C)The mutation prevents ribosome binding by altering sequences of the HOX3A mRNA.
• D)The mutation increases transcription of an miRNA that has sequence homology to the HOX3A gene.

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Definitions:

Between-Group Variance

Between-group variance refers to the variation in data points that can be attributed to the differences in conditions or treatments across groups in an experiment.

Within-Group Variance

The measure of variability of data within a single group, reflecting how spread out the data points are around the group mean.

SSA

SSA stands for Social Security Administration, a government agency overseeing social security, a social insurance program consisting of retirement, disability, and survivors benefits.

SSB

Sum of Squares Between, a measure used in statistical analysis to describe the variability between groups.