SNPs Can Be Detected by Microarrays, Which Are Wafer-Like Substrates

question 20

Multiple Choice

SNPs can be detected by microarrays, which are wafer-like substrates to which millions of short stretches of DNA are attached. A microarray consists of many different squares, each one containing a different sequence of single-stranded DNA to which fluorescently labeled strands of DNAs from patients with different SNPs can hybridize. If one square will hybridize with an SNP having a C-G base pair at a particular site and an adjacent square will hybridize with an SNP having a T-A base pair at the same site, which of the following genotypes will hybridize with both squares and make them fluoresce?

• A)the homozygous C-G/C-G genotype
• B)the homozygous T-A/T-A genotype
• C)the heterozygous C-G/T-A genotype
• D)None of the answer options is correct; all of the genotypes hybridize with both squares.

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Definitions:

Offshoring

The relocation of a business process or operation from one country to another, typically to exploit lower labor costs or favorable regulatory environments.

Shipping Costs

Expenses associated with transporting goods from one location to another.

Raw Material Costs

Expenses associated with acquiring the unprocessed materials needed to manufacture a product. These costs are a significant component of total production cost.

Total Cost Of Offshoring

The comprehensive calculation of all expenses related to relocating business operations abroad, including setup, operational, and labor costs.