In the Sickle-Cell Anemia Mutation, the 5-GAG-3 Codon

question 141

Multiple Choice

In the sickle-cell anemia mutation, the 5-GAG-3 codon for glutamic acid becomes the 5-GUG-3 codon for valine. Assuming a single nucleotide substitution accounts for this mutation, what is the change in the DNA?

• A)5  -CTC-3  /3  -GAG-5  to 5  -CAC-3  /3  -GTG-5 
• B)3  -CTC-5  /5  -GAG-3  ' to 5  -CAC-3  /3  -GTG-5 
• C)5  -CTC-3  /3  -GAG-5  to 3  -CAC-5  /5  '-GTG-3  '
• D)3  -CTC-5  /5  -GAG-3  ' to 3  -CAC-5  /5  -GTG-3 

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Definitions:

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