A Shotgun Genome Sequencing Project Is Designed in Which the Average

question 51

Multiple Choice

A shotgun genome sequencing project is designed in which the average length of a sequenced fragment is 100 nucleotides and each nucleotide is to be sequenced an average of 30 times. For the human genome, which is 3 × 10⁹ base pairs long, how many fragments of 100 nucleotides would need to be sequenced?

• A)(3 × 10⁹)× 30 × 100 = 9 × 10¹¹
• B)(3 × 10⁹)× 30 ÷ 100 = 9 × 10⁸
• C)(3 × 10⁹)× 100 ÷ 30 = 1 × 10¹⁰
• D)(3 × 10⁹)÷ (30 × 100)= 1 × 10⁶

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