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A Cell with a Defect in the Proofreading Function of DNA

question 155

Multiple Choice

A cell with a defect in the proofreading function of DNA polymerase is observed to have a rate of incorporation of incorrect bases into newly synthesized DNA that is 100 times greater than a cell with a nondefective, normal DNA polymerase. Estimate from this number what fraction of incorrect nucleotide incorporations are corrected by the proofreading function of DNA polymerase in the cell with normal DNA polymerase.


Definitions:

Low Speed Shimmy

A condition where a vehicle's steering wheel oscillates or vibrates at low speeds, often indicating issues with wheel alignment, balance, or suspension components.

Darting

Unpredictable, sudden movements of a vehicle from side to side, often caused by inconsistent road surfaces or improper alignment.

Toe-in

It refers to the alignment adjustment of vehicle wheels in which the front of the tires are closer to each other than the rear, promoting straight-line stability.

Feather-edge Wear

Wear pattern on tires or brakes characterized by a tapered condition where one edge is significantly thinner than the opposite edge, often resulting from improper alignment.

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