Suppose There Is a Mutation in a Laminin-Binding Integrin Gene

question 122

Multiple Choice

Suppose there is a mutation in a laminin-binding integrin gene that causes a loss of function in the cytoplasmic domains of the integrin. Which one of the following would you expect to observe as a result of this mutation?

• A)The strength of tissues would be decreased because the integrin could no longer associate with intermediate filaments in hemidesmosomes.
• B)The integrin would function normally because the cytoplasmic domain is not responsible for binding to laminin.
• C)Cell adhesion to laminin would decrease, but laminin-meditated gene expression would remain the same.

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Definitions:

Collective Efficacy

The shared belief in a group's capability to organize and execute the courses of action required to produce given levels of achievements.

Cohesion

The degree of camaraderie and unity among members of a group or team, often contributing to its success.

Sherifs' Studies

Refers to a series of experiments on group conflict and cooperation by social psychologist Muzafer Sherif, emphasizing the ease of inducing group antagonism and the methods of resolving it.

Relational Cohesion Theory

A theoretical framework that explains how relationship quality and trust are developed in groups and organizations, focusing on the cohesion among members.