Suppose There Is a Mutation in a Laminin-Binding Integrin Gene

question 62

Multiple Choice

Suppose there is a mutation in a laminin-binding integrin gene that causes a loss of function in the cytoplasmic domains of the integrin. Which of the following would you expect to observe as a result of this mutation?

• A)The integrin would be unable to signal the cytoplasm when it had bound to laminin.
• B)The integrin would function normally because the cytoplasmic domain is not responsible for binding to laminin.
• C)Tissues would be weakened because the integrin could no longer associate with microfilaments in adherens junctions.
• D)Cell adhesion to laminin would decrease, but laminin-meditated gene expression would remain the same.

---

Definitions:

Wilhelm Wundt

Known as the father of experimental psychology, he founded the first formal laboratory for psychological research at the University of Leipzig in 1879.

Biopsychosocial Perspective

An interdisciplinary model that examines human health and disease across biological, psychological, and social factors.

Evolutionary Perspective

An approach in psychology that emphasizes the role of evolution and natural selection in shaping behaviors, traits, and psychological mechanisms.

William James

An American philosopher and psychologist, often considered the father of American psychology, who made significant contributions to early psychology and philosophy.