Derivatives of the Compound Shown Below Are Currently Being Examined

question 111

Multiple Choice

Derivatives of the compound shown below are currently being examined for their effectiveness in treating drug addiction and metabolic syndrome (J. Med. Chem. 2006, 872) . Which sequence ranks the following aromatic rings of this compound in order of increasing reactivity in an electrophilic aromatic substitution reaction (slowest to fastest reacting) ?

• A) 1 < 2 < 3
• B) 2 < 3 < 1
• C) 3 < 2 < 1
• D) 3 < 1 < 2
• E) 2 < 1 < 3

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Definitions:

White Pulp

Part of the spleen consisting of lymphatic nodules and diffuse lymphatic tissue; associated with arteries.

Spleen

Large lymphatic organ in the upper part of the abdominal cavity on the left side between the stomach and diaphragm, composed of white and red pulp. It responds to foreign substances in the blood, destroys worn-out red blood cells, and is a storage site for blood cells.

Immune Response

The body's defense mechanism against pathogens, involving recognition and destruction of harmful substances or organisms.

Dense Connective Tissue

A type of connective tissue that is rich in collagen fibers, providing strength and elasticity.