To Find Gene(s) Involved in the Drosophila Period Phenotype Investigators

question 15

Multiple Choice

To find gene(s) involved in the Drosophila Period phenotype investigators used 'forward genetics'. What does this mean?

• A) The investigators knew the Period gene was involved in circadian rhythms and so used homologous recombination to knock-out the gene and found the circadian rhythm was altered.
• B) The investigators thought the Period gene was involved in circadian rhythms and made a conditional knockout of the Period gene using the Cre/lox system. When the Period protein was knocked out the flies displayed a disrupted circadian rhythm.
• C) The investigators used random mutagenesis to find animals with the Period phenotype and used molecular genetic methods (such as positional cloning) to identify the gene.
• D) The investigators used the CRISPR/Cas9 system to selectively manipulate the Period gene and confirmed this by showing a disrupted circadian rhythm in the flies.

Distinguish between different types of analysis including scenario, sensitivity, and simulation analyses in evaluating project variables.

Understand the concept of the cost of capital and its impact on investment returns and valuation.

Identify the components of capital and their respective costs.

Explain the differences in cost between debt and equity financing.

---

Definitions:

Meeting

A gathering of individuals or representatives for the purpose of discussing and acting upon matters of common interest.

Incorporators

Individuals who sign the articles of incorporation for a corporation, effectively bringing it into existence under the law.

Corporate Articles

Legal documents filed with a state government to formally establish the existence of a corporation.

Incorporation

The process of legally declaring a corporate entity as separate from its owners.