In the Experiment in Figure , the Motor Neuron of a Muscle

question 22

Multiple Choice

In the experiment in Figure , the motor neuron of a muscle expressed the P2X₂ transgene and the response in the muscle was recorded. Why did application of ATP activate the muscle? Figure

• A) Addition of ATP activated of the P2X₂ channel which directly increased transmitter release by moving vesicles to the presynaptic membrane.
• B) Addition of ATP resulted in opening of the P2X₂ channel and an influx of sodium, which activated the motor neuron, releasing neurotransmitter and activation of the muscle.
• C) Addition of the resulted in activation of the P2X₂ protein, a G protein coupled receptor. Once activated the receptor increased the probability of neurotransmitter release and activated the muscle.
• D) Addition of ATP resulted in activation of the ATP receptor, a G protein coupled receptor. Once activated, this G protein indirectly activated P2X₂, which increased the probability of neurotransmitter release from the motor neuron and activated the muscle.

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