In the 1990s, Drug Users Started Developing Parkinson's Like Symptoms

question 13

Multiple Choice

In the 1990s, drug users started developing Parkinson's like symptoms. It was found that a contaminant, called MPTP, was in an opioid-like drug. How does MPTP cause Parkinson's like symptoms?

• A) MPP⁺ inhibits mitochondrial function in dopaminergic neurons.
• B) MPTP inhibits mitochondrial function in dopaminergic neurons.
• C) MPTP increases the enzymatic activity of monoamine oxidase with increases the number of free radicals in dopaminergic neurons.
• D) MPP⁺ blocks the release in dopamine from dopaminergic neurons, specifically from the substantia nigra.

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