Rett Syndrome Is Caused by Mutation in an X-Linked Gene

question 26

Multiple Choice

Rett syndrome is caused by mutation in an X-linked gene called MeCP2. Why does mutation of this one gene cause so many neurological defects?

• A) CeCP2 regulates protein synthesis by global phosphorylation of protein kinases.
• B) CeCP2 causes irregular protein folding in a ubiquitous neural protein.
• C) CeCP2 binds to methylated DNA and regulates gene expression.
• D) CeCP2 is a histone that controls epigenetic regulation of gene expression.

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