There Are Three Robo Genes (Robo, Robo2, and Robo3) Encoding

question 3

Essay

There are three Robo genes (Robo, Robo2, and Robo3) encoding receptors for Slit, which acts as a midline repellant. In homozygous Slit mutant embryos, all axons collapse at the midline, while in homozygous Robo mutant embryos, axons re-cross the midline, resulting in thinner longitudinal tracts and thicker commissures (Figure Q7-8). Figure Q7-8
What would you expect the ventral nerve cord phenotype of a triple Robo mutant (loss of function of all three Robo genes) to be? Briefly explain your reasoning.

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Definitions:

Stoma

A surgically created opening on the body’s surface to allow for the elimination of waste, commonly associated with procedures like colostomies.

Mucus

A thick, slippery substance produced by mucous membranes and glands to moisturize and protect certain parts of the body.

Constipation

A common digestive condition characterized by infrequent bowel movements, difficulty passing stools, or experiencing incomplete evacuations.

Bowel Movement

The act of expelling feces from the digestive tract through the anus.