When the P2 Coding Region Is Replaced by IRES-Tau-LacZ Alone

question 20

Essay

When the P2 coding region is replaced by IRES-tau-lacZ alone, the pattern of expression in the epithelium is indistinguishable from wild type, but the axons wander through the outer nerve layer, failing to converge to any particular region or glomerulus, once they enter the olfactory bulb. What can be inferred from this experiment?

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