Examlex
Fill in each of the blanks with the best word or phrase selected from the list below. Not all words or phrases will be used; each word or phrase should be used only once.
The axon growth cone contains two prominent actin structures: _____________ are composed of bundled F-actin, whereas _____________ are a meshwork of branched F-actin. Many axon guidance cues affect the actin cytoskeleton through their receptors and downstream effectors such as the _____________ Rho, Rac, and Cdc42. These molecules are activated by _____________ and inactivated by _____________. For example, in the context of ephrin-A to EphA _____________ signaling, a GEF called ephexin was shown to mediate growth cone _____________ by linking the EphA receptor to RhoA.
collapse guanine nucleotide exchange factors (GEFs)
filopodia lamellipodia
forward reverse
G-protein-coupled receptors (GPCRs) small GTPases
GTPase activating proteins (GAPs) stabilization
Corticotropin-Releasing Hormone
A peptide hormone involved in the stress response, stimulating the release of ACTH from the pituitary gland.
Anterior Pituitary
The front portion of the pituitary gland, responsible for producing and releasing hormones that regulate various bodily functions.
Adrenocorticotropic Hormone
Adrenocorticotropic hormone (ACTH) is a peptide hormone produced by the anterior pituitary gland that stimulates the adrenal cortex to release cortisol and other steroid hormones.
Steroid Hormones
Biologically active molecules derived from cholesterol that play crucial roles in various body functions, including growth, metabolism, and immune response.
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