Our visual system has a remarkable dynamic range. When you go to a matinee movie (during the daytime) and walk out of the theater it is difficult to see. After a few minutes your eyes adapt to the new light levels. Some of the molecular mechanisms of light adaptation are known and most involve changes in Ca2+ concentration. (A)
(B)
Figure Q4-13
A. Based on the data from the experiments shown in Figure Q4-13, what is one mechanism of adaptation? Figure Q4-13A shows the dark-adapted response to a flash of light in wild type and GCAP knockout mice. Figure Q4-13B shows the rod response to a flash of light relative to the same flash after dark adaptation.
B. What is the probable molecular mechanism of reduced light adaptation involving GCAP?
Definitions:
Cyclohexanone
An organic compound with the formula (CH2)5CO, characterized by a six-carbon ring with a ketone functional group.
Benzophenone
An organic compound with the formula (C6H5)2CO, commonly used in organic chemistry as a photoinitiator.
Diethyl Ether
An organic compound commonly used as a solvent, characterized by an oxygen atom connecting two ethyl groups.
1-Butanol
A primary alcohol with the chemical formula C4H9OH, characterized by a four-carbon straight chain terminating in a hydroxyl group.
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