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Norepinephrine (NE) can bind to the β-adrenergic receptor and speed up heart rate through the cAMP signaling cascade. The cAMP cascade results in the phosphorylation of a voltage-gated Ca2+ channel, which increases its open probability. For each situation below state if the Ca2+ channel open probability increases, decreases, or does not change.
A. Intracellular addition of cAMP, in the absence of application of NE
B. In the absence of NE application, the inability of GTP to dissociate from Gα
C. In the presence of NE application, the inability of GDP to dissociate from Gα
Organization Characteristics
Attributes or features that define the distinctive nature and functioning of an organization, such as its culture, structure, and management practices.
External Environment
Involves the surrounding conditions, forces, or circumstances outside an organization that affect its operations and strategies.
Socioeconomic Factors
Aspects relating to an individual's social and economic position that affect their health and well-being, such as income, education, and employment.
Health Community
A group of people and organizations working together to improve public health and wellness.
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