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Exhibit 23-8
Consider the compound 2-methyl-2-carboethoxycyclopentanone,whose structure is shown below,to answer the following question(s).
-Refer to Exhibit 23-8.When 2-methyl-2-carboethoxycyclopentanone is treated with sodium ethoxide in ethanol solution followed by a mild aqueous acid work-up,5-methyl-2-carboethoxycyclopentanone is isolated as the major product.This reaction proceeds by a reverse Claisen condensation mechanism followed by a recyclization.On the structures provided below,show electron flow with arrows in this interesting reaction.
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