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Exhibit 23-3
Consider the data below to answer the following question(s):
The Friedlander Quinoline Synthesis,first reported in 1882,is the base-catalyzed condensation of 2-aminobenzaldehydes with ketones to form quinoline derivatives.
-Refer to Exhibit 23-3.The second step of the Friedlander Quinoline Synthesis is a nucleophilic addition of a primary amine to a ketone yielding an imine.Write the complete stepwise mechanism for this imine forming reaction.Show all electron flow with arrows and show all intermediate structures.
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Q22: Refer to Exhibit 16-6.Attempts to prepare isobutylbenzene
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Q36: Consider the following MO diagram for a
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