Carbamazepine Has a Black Box Warning Recommending Testing for the HLA-B*1502

question 5

Multiple Choice

Carbamazepine has a Black Box warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to:

• A) Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 allele
• B) Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele
• C) Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele
• D) Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine

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Definitions:

Gene Flow

The introduction of alleles from the gene pool of one population into that of another.

Political Category

A classification used in political science to delineate different kinds of political actions, policies, or actors.

Social Category

A group of people who share a common characteristic or attribute, which is often used to classify them within societal structures.

Public Display

The act of presenting or showcasing something or someone to the general public or an audience.