On the Enzyme Hexokinase, ATP Reacts with Glucose to Produce

question 26

Essay

On the enzyme hexokinase, ATP reacts with glucose to produce glucose 6-phosphate and ADP five orders of magnitude faster than ATP reacts with H₂O to form phosphate and ADP. The intrinsic chemical reactivity of the -OH group in water is about the same as that of the glucose molecule, and water can certainly fit into the active site. Explain this rate differential in two sentences or less.

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Definitions:

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Functional Magnetic Resonance Imaging

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Amygdala

A section of the brain that is crucial for emotion regulation, particularly fear and pleasure responses.

Inhibited

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