The Synthesis of Purine and Pyrimidine Nucleotides Differ in That

question 26

Multiple Choice

The synthesis of purine and pyrimidine nucleotides differ in that:

• A) ATP is required in the synthesis of purines but not in the synthesis of pyrimidines.
• B) purine biosynthesis starts with the formation of PRPP, whereas pyrimidines incorporate the PRPP near the end of the pathway.
• C) purine formation requires a THF derivative, whereas pyrimidine formation does not.
• D) pyrimidine biosynthesis is tightly regulated in the cell, whereas purine biosynthesis is not.
• E) pyrimidines go through many steps, adding a single carbon or nitrogen each time, whereas the basic skeleton for purines is formed by two main precursors.

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