Which of the Following May Result in Loss of Function

question 1

Multiple Choice

Which of the following may result in loss of function of a tumor suppressor gene?

• A)Nondisjunction of sister chromatids
• B)Failure of a chromatid containing a tumor suppressor gene to attach to a spindle fiber during cell division
• C)Hypermethylation of the promoter for the gene
• D)A,B,and C
• E)None of the above

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Definitions:

Initial Investment

The amount of money used to start a project, venture, or purchase an investment, before any returns or profits are considered.

Project Profitability Index

The ratio of the net present value of a project’s cash flows to the investment required.

Internal Rate

Typically refers to the Internal Rate of Return (IRR), a financial metric used to estimate the profitability of potential investments.

Discount Rate

The interest rate used in discounted cash flow analysis to determine the present value of future cash flows.