Explain Why It Is Necessary to Match at Least Some

question 64

Essay

Explain why it is necessary to match at least some of the HLA allotypes between donor and recipient in a bone marrow transplant given to remedy SCID.

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Definitions:

Anger

A strong feeling of displeasure or hostility, often arising in response to perceived wrong or injustice.

Adrenocorticotropic Hormone

A hormone produced by the pituitary gland that stimulates the adrenal cortex to secrete cortisol and other hormones.

Adrenal Cortex

The outer portion of the adrenal gland that produces steroid hormones which regulate carbohydrate and fat metabolism, as well as mineralocorticoids that regulate salt and water balance in the body.

Corticosteroids

A class of steroid hormones that are produced in the adrenal cortex of vertebrates and are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation.