Negative Selection of Developing B Cells Ensures That

question 12

Multiple Choice

Negative selection of developing B cells ensures that

• A)there is not an overabundance of circulating B cells that would compete with other important cell types in the circulation
• B)only antigen-activated B cells leave the bone marrow
• C)clonal expansion of B cells does not occur in the absence of infection
• D)B-cell receptors that bind to normal constituents of the body do not emerge
• E)B cells do not leave secondary lymphoid tissues.

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Definitions:

Schizophrenia

A chronic and severe mental disorder characterized by distortions in thinking, perception, emotions, language, sense of self, and behavior.

State Mental Hospitals

Publicly funded psychiatric hospitals primarily responsible for treating individuals with severe mental health disorders, often when less restrictive settings are inadequate.

Mid-Twentieth Century

Pertains to the period around the middle of the 20th century, typically considered to span from the 1930s to the 1960s.

State Hospitals

Public hospitals administered by the government, often specifically for mental health care, rehabilitation, or long-term illness.