What Evidence Supports the Proposal That MHC Diversity Evolved by Natural

question 32

Essay

What evidence supports the proposal that MHC diversity evolved by natural selection caused by infectious pathogens rather than exclusively by random DNA mutations?

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Definitions:

α-D-Fructofuranose

An isomer of fructose where the furanose ring form predominates, characterized by its specific configuration at the anomeric carbon.

Methyl Glycoside

Glycosides formed by the reaction of a sugar with methanol, characterized by a methoxy group replacing the glycosidic hydroxyl group of the sugar.

Mutarotation

The change in optical rotation due to the change in equilibrium between two anomers of a sugar solution over time.

Methyl-β-D-Talopyranoside

A chemical compound that is a methyl glycoside derived from the β-anomer of D-talopyranose.