A Patient with Systemic Lupus Erythematosus (SLE) Shows Evidence of Decreased

question 11

Multiple Choice

A patient with systemic lupus erythematosus (SLE) shows evidence of decreased hemoglobin and ongoing hemolysis. The DAT is negative. Which of the following is the most likely explanation for these results?

• A) The subclass of IgG is not recognized by the polyspecific AHG.
• B) The thermal amplitude of the antibody is <37°C.
• C) High-dose IVIG used in treatment is interfering with the binding of AHG.
• D) There is insufficient IgG for detection.

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