With Reference to Aberrant Methylation of Bases Which of the Following

question 25

Multiple Choice

With reference to aberrant methylation of bases which of the following statements, if any, is false?

• A) S-adenosylmethionine donates methyl groups to a range of different molecules in cells and frequently inappropriately methylates bases in DNA.
• B) Guanine is occasionally methylated to give O-6-methylguanine which base pairs with adenine rather than with cytidine.
• C) In each nucleated cell, about 300-600 adenines are converted to 3-methyladenine per day.
• D) 3-methyladenine can be a cytotoxic base: it distorts the double helix and that can disrupt crucial DNA-protein interactions.

Understand the relationship between Earth's climate changes and biological evolution.

Describe the process and effects of subduction in plate tectonics.

Distinguish between weather and climate in the context of long-term geological timelines.

Understand the importance of prokaryotes in Earth's oxygenation and its implications for life's evolution.

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