A Mutant Bacterial Cell Has a Defective Aminoacyl- TRNA Synthetase

question 14

Multiple Choice

A mutant bacterial cell has a defective aminoacyl- tRNA synthetase that attaches a lysine to tRNAs with the anticodon AAA instead of the normal phenylalanine. What would the consequence of this be for the cell?

• A) None of the proteins in the cell will contain phenylalanine.
• B) The ribosome will skip a codon every time a UUU is encountered.
• C) The cell will compensate for the defect by attaching phenylalanine to tRNAs with lysine- specifying anticodons.
• D) Proteins in the cell will include lysine instead of phenylalanine at amino acid positions specified by the codon UUU.
• E) The ribosome will stall whenever an abnormal lysine tRNA binds to the A site.

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