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A Culture of Insulin-Responsive Cells Are Analyzed After Stimulation with Insulin.The

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A culture of insulin-responsive cells are analyzed after stimulation with insulin.The insulin receptors are then isolated (assume that during the isolation protocol the insulin is removed from the receptor).Half of the sample is analyzed by SDS-PAGE followed by Coomassie blue staining.The other half of the sample is analyzed via SDS-PAGE followed by a Western blot.The primary antibody used in the blot recognizes phosphorylated tyrosine residues.Predict how many bands will be seen on the SDS-PAGE compared with the Western blot and explain your answer.


Definitions:

Interaction

The effect of two or more variables is not simply additive, but depends on the levels of the other variables.

Factorial ANOVA

A statistical test used to examine the effects of two or more independent variables on a dependent variable, and their interactions, within an experimental design.

Probability Level

The threshold of significance in hypothesis testing, indicating the likelihood that a result is not due to chance.

Main Effect

The direct influence of an independent variable on a dependent variable in an experiment, ignoring other factors or interactions.

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