A Mutation in The $\beta$ Subunit of Hemoglobin Is Discovered That Reduces the Affinity of That

question 79

Multiple Choice

A mutation in the $\beta$ subunit of hemoglobin is discovered that reduces the affinity of 2,3-BPG binding. Which of the following mutations is most likely to have this consequence?

• A) Val1 \(\rightarrow\) Ile1
• B) Asp99 \(\rightarrow\) Glu99
• C) Lys82 \(\rightarrow\) Asp82
• D) Glu6 \(\rightarrow\) Val6

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Definitions:

Relapse

Repeated drug use and/or alcohol use after a period of improvement from substance abuse.

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The act of refraining from engaging in certain behaviors or indulging in substances, such as alcohol or sex.

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Middle-aged

A period of adulthood that typically describes individuals aged between 45 and 65, often characterized by stability, maturity, and increased responsibilities.