The Two Main COMT-Inhibitory Drugs Tolcapone (Tasmar)and Entacapone

question 78

Multiple Choice

The two main COMT-inhibitory drugs tolcapone (Tasmar) and entacapone:

• A) inhibit peripheral COMT but not in the CNS.
• B) enhance central COMT but not in the PNS.
• C) enhance COMT in both the PNS and CNS.
• D) have no effect on COMT in either the PNS nor CNS.

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Definitions:

Delta

A landform created by the deposition of sediment carried by a river as the flow leaves its mouth and enters slower-moving or stagnant water.

River Terraces

Flat, bench-like surfaces adjacent to the course of a river, which indicate previous river levels and can be used to reconstruct past environmental changes.

River Terraces

Stepped, flat surfaces alongside river valleys that represent previous levels of the river bed, formed by river erosion and changes in water level.

Nile River

The longest river in Africa, flowing north through northeastern Africa to drain into the Mediterranean Sea.