The Concentration of a Particular Protein, X, in a Normal

question 23

Multiple Choice

The concentration of a particular protein, X, in a normal human cell rises gradually from a low point, immediately after cell division, to a high point, just before cell division, and then drops sharply.The level of its mRNA in the cell remains fairly constant throughout this time.Protein X is required for cell growth and survival, but the drop in its level just before cell division is essential for division to proceed.You have isolated a line of human cells that grow in size in culture but cannot divide, and on analyzing these mutants, you find that levels of X mRNA in the mutant cells are normal.Which of the following mutations in the gene for X could explain these results?

• A)the introduction of a stop codon that truncates protein X at the fourth amino acid
• B)a change of the first ATG codon to CCA
• C)the deletion of a sequence that encodes sites at which ubiquitin can be attached to the protein
• D)a change at a splice site that prevents splicing of the RNA

Learn how SWOT analysis and environmental scanning contribute to new-product strategy development and the overall new-product development process.

Understand the concept testing phase and its role in evaluating new-product ideas before moving to the actual production phase.

Comprehend various strategies firms adopt to generate new-product ideas including crowdsourcing and its impact on innovation.

Recognize the importance of customer experience management (CEM) in designing and delivering products that meet consumer expectations.

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Definitions:

Charles Handy

An Irish author and philosopher specializing in organizational behavior and management who is known for his theories on the changing shape of work and organizations.

Traditional Career Path

A linear progression in one's professional life, typically involving successive roles within the same field or industry.

Core Worker

An employee who is considered essential to the operations of a business, often providing critical skills or functions.

Charles Handy

A respected British management thinker known for his theories on organizational culture and motivation.