You Are Interested in Understanding the Gene Regulation of Lkp1

question 24

Multiple Choice

You are interested in understanding the gene regulation of Lkp1, a protein that is normally produced in liver and kidney cells in mice.Interestingly, you find that the LKP1 gene is not expressed in heart cells.You isolate the DNA upstream of the LKP1 gene, place it upstream of the gene for green fluorescent protein (GFP) , and insert this entire piece of recombinant DNA into mice.You find GFP expressed in liver and kidney cells but not in heart cells, an expression pattern similar to the normal expression of the LKP1 gene.Further experiments demonstrate that there are three regions in the promoter, labeled A, B, and C in Figure 8-16, that contribute to this expression pattern.Assume that a single and unique transcription factor binds each site such that protein X binds site A, protein Y binds site B, and protein Z binds site C.You want to determine which region is responsible for tissue-specific expression, and create mutations in the promoter to determine the function of each of these regions.In Figure 8-16, if the site is missing, it is mutated such that it cannot bind its corresponding transcription factor. Figure 8-16
Which of the following proteins are likely to act as gene activators?

• A)factors X and Y
• B)factors X and Z
• C)factors Y and Z
• D)factor X only

Use correct tense in sentences.

Distinguish between incorrect adjective-adverb use.

Correct spelling mistakes.

Apply basic principles of capitalization correctly.

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Definitions:

Total Manufacturing Costs

The complete sum of expenses related to producing goods, including labor, materials, and overhead.

Cost of Goods Manufactured

The total cost incurred by a company to produce goods in a specific period, including materials, labor, and overhead.

Overhead Account

An accounting category used to record all indirect costs associated with the production process, such as utilities, rent, and administrative expenses.

Actual Overhead Cost

The actual expenses incurred for overhead in the manufacturing or production process, including costs related to indirect materials, labor, and other indirect expenses.