Three Loci, Mitochondrial Malate Dehydrogenase That Forms a and B

question 6

Essay

Three loci, mitochondrial malate dehydrogenase that forms a and b (MDHa, MDHb), glucuronidase that forms 1 and 2 (GUS1, GUS2), and a histone gene that forms + and -
(H^{+, H-}), are located on chromosome #7 in humans. Assume that the MDH locus is at position 35, GUS at position 45, and H at position 75. A female whose mother was homozygous for MDHa, GUS2, and H⁺ and whose father was homozygous for MDHb, GUS1, and H^- produces a sample of 1000 egg cells. Give the genotypes and expected numbers of the various types of cells she would produce. Assume no chromosomal interference.

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