Dentinogenesis Imperfecta Is a Rare,autosomal,dominantly Inherited Disease of the Teeth

question 38

Essay

Dentinogenesis imperfecta is a rare,autosomal,dominantly inherited disease of the teeth that occurs in about one in 8000 people (Witkop 1957).The teeth are somewhat brown in color,and the crowns wear down rapidly.Assume that a male with dentinogenesis imperfecta and no family history of the disease marries a woman with normal teeth.What is the probability that
a) their first child will have dentinogenesis imperfecta?
b) their first two children will have dentinogenesis imperfecta?
c) their first child will be a girl with dentinogenesis imperfecta?

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Definitions:

Amygdala

A section of the brain's limbic system involved in processing emotions, emotional behavior, and motivation, notably fear and pleasure responses.

Cerebellum

A part of the brain located at the back of the skull that is responsible for coordinating and regulating voluntary movements.

Brain Regions

Specific areas within the brain that have distinct functions, such as the prefrontal cortex which is involved in decision making and personality development.

Limbic System

A complex system of nerves and networks in the brain, involved in emotions such as fear and pleasure, as well as instincts and mood.