How Can Microarrays Differentiate Between a Wild-Type Allele and a Disease

question 38

Multiple Choice

How can microarrays differentiate between a wild-type allele and a disease allele that differ at only one nucleotide?

• A)The DNA sequences of both alleles are determined.
• B)Oligonucleotides hybridize with the two alleles differently.
• C)Polymerase chain reaction primers amplify DNA from one allele, but not the other.
• D)Microarrays are not capable of detecting a difference between those alleles.

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