What Do You Predict Would Be the Effect of an Inversion

question 18

Multiple Choice

What do you predict would be the effect of an inversion of the β-globin gene cluster with respect to the LCR?

• A)No globin genes will be expressed and the fetus will die in utero.
• B)ε-globin will be expressed first during development.
• C)The order of globin gene expression will be reversed; the effect on the fetus cannot be predicted.
• D)The individual will develop sickle-cell disease in adult life.

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