In HLA Serologic Testing, How Are Cytotoxic Effects of Antigen-Antibody

question 1

Multiple Choice

In HLA serologic testing, how are cytotoxic effects of antigen-antibody interactions detected?

• A) There is visible agglutination, or clumping.
• B) The cells remain clear.
• C) Trypan blue or eosin stains the cells because of loss of membrane integrity.
• D) There is hemolysis.

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Definitions:

T Distribution

A probability distribution used in statistics that accounts for the sample size in estimating the mean of a normally distributed population when the standard deviation is unknown.

One-tailed Test

A statistical test in which the region of rejection is on only one side of the sampling distribution, used when predicting the direction of a potential difference or relationship.

Sample Size

The number of observations or subjects selected from a population for a study.

T Distribution

A statistical distribution used when the sample size is small and the population standard deviation is unknown.