A Platelet Recipient Whose HLA Phenotype Includes A3, B7; A11

question 20

Multiple Choice

A platelet recipient whose HLA phenotype includes A3, B7; A11, B42 is transfused from a A1, B7; A3, B13 donor. Given the following CREG (Cross-Reactive Groups) , what would you expect the outcome of this transfusion to be? A1-CREG: A1,36,3,9(23,24) ,10(25,26,34,66) ,11, 19(29,30,31,32,33) 28 B7-CREG: B7,42,22(54,55,56) ,27,40(60,61) 13,41,47,48

• A) The donor would experience platelet refractoriness because A3 and A11 and B13 and B42 are not cross-reactive.
• B) The donor would benefit from this transfusion because A3 and A11 and B13 and B42 are cross-reactive.
• C) The recipient would experience platelet refractoriness because A3 and A11 and B13 and B42 are not cross-reactive.
• D) The recipient would benefit from this transfusion because A3 and A11 and B13 and B42 are cross-reactive.

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