How Does Inactive MLH1 Contribute to the Development of Some

question 11

Multiple Choice

How does inactive MLH1 contribute to the development of some forms of inherited colon cancer?

• A) It results in the deletion of a nucleotide repeat in the DUX4 gene.
• B) DNA damage is left unrepaired.
• C) There is an expansion in the number of cytosine-guanine (CG) dinucleotide.
• D) Downregulation of IGF2 occurs.

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