What Is a Major Difference in Using Lod-Score Analysis Compared

question 60

Multiple Choice

What is a major difference in using lod-score analysis compared to using association studies in determining gene locations in humans?

• A) Lod-score analysis relies on family or pedigree data, while association studies use population data.
• B) Lod-score analysis requires that the loci being mapped must be on different chromosome arms, while association studies can map genes on different chromosomes.
• C) Association studies compare genotypes between parents and their children, while lod-score analysis compares genotypes between siblings of the same family.
• D) Lod-score analysis requires isolated human populations, while association studies require very large family pedigrees.
• E) Lod-score analysis requires a large number of genes with multiple alleles, while association studies can use genes that have only two alleles.

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Definitions:

Central Focus

The primary or most important point of attention or activity.