The Results of Linkage Analysis for DNA Marker a and the P53

question 54

Multiple Choice

The results of linkage analysis for DNA marker A and the p53 gene are shown below. What is the best estimate for the approximate genetic distance between marker A and the p53 gene in humans? $$\begin{array} { c c c c c c c } \text { Recombination values (m.u.) } & 1 & 5 & 10 & 20 & 30 & 40 \\\text { lod score } & 2.13 & 2.54 & 3.14 & 4.10 & 4.96 & 3.22\end{array}$$

• A) 1 m.u.
• B) 5 m.u.
• C) 10 m.u.
• D) 20 m.u.
• E) 30 m.u.

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