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Activin Is a Protein That Normally Exists in a Gradient

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Activin is a protein that normally exists in a gradient within certain tissues in developing embryos. Certain undifferentiated cells cultured without activin produce epidermal cells. However, activin induces these same cells to adopt other fates (e.g., blood, muscle, heart) , depending on the concentration of activin. Based on these observations, activin acts as a(n) :


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