Use the Following to Answer Questions
the Following Microarray $\bullet$

question 15

Multiple Choice

Use the following to answer questions
The following microarray data are shown for four human genes. Two samples were hybridized to the microarray in this experiment. One sample was cDNA generated from mRNA of a tissue culture cell line that was originally derived from a B-cell leukemia. The other sample was cDNA generated from normal, mature neural tissue.
$\bullet$ Vertical stripes mean hybridization to cancerous B-cell cDNA only.
$\bullet$ Horizontal stripes mean hybridization to normal neural cell cDNA only.
$\bullet$ Completely filled in means hybridization to both cDNA types.
$\bullet$ Blank means hybridization to neither cell's cDNA.
-One spot on the microarray contains sequences unique to a gene for an RNA polymerase subunit. One spot contains sequences unique to the skeletal muscle myosin gene. Which spot would be expected to contain the myosin gene sequences?

• A) spot 1
• B) spot 2
• C) spot 3
• D) spot 4
• E) none of the spots

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Definitions:

Problem-focused Coping

A strategy for managing stress by directly tackling the problem that is causing the stress.

Immune System

The body's defense mechanism against infections and diseases through a complex network of cells, tissues, and organs.

Physiological Effects

Changes in the normal functions of the body that can result from various factors, including stress, dietary habits, and environmental changes.

Problem-focused Coping

A strategy involving directly addressing a problem by finding solutions to alter the source of stress.