Use the Following to Answer Questions

question 58

Multiple Choice

Use the following to answer questions
You identify an RFLP in mice by digesting genomic DNA with HindIII enzyme and radiolabeling a piece of probe DNA. Southern blot analysis shows that the probe detects a 2-kb fragment in one strain of mice and a 4-kb fragment in another strain of mice. The two mice strains are crossed to produce an F₁ generation. Two F₁ siblings are mated to produce a dozen F₂ progeny. You isolate genomic DNA from several F₁ and F₂ individuals, digest with HindIII, and perform a Southern blot with the same probe.
-How many bands would be seen in the Southern blot of an F₂ individual?

• A) one
• B) two
• C) three
• D) four
• E) one or two

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Definitions:

Sampling Distribution

The chance distribution of a statistical measure derived from numerous samples taken from a particular group.

Central Limit Theorem

A theory stating that when samples are large enough, their mean will be approximately normally distributed, regardless of the population's distribution.

Standard Error

A statistical measure that quantifies the variability or dispersion of a sample statistic from the population parameter it estimates.

Population Distribution

A term that describes how the values of a variable are distributed across an entire population.