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an Auxotrophic E

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An auxotrophic E. coli strain requires adenine to grow because of a mutation in a gene for an adenine synthesis enzyme. The following shows part of the wild-type and mutant alleles of the gene, including the start codon. The bottom strand is the template for transcription.  ade 1+wild-type allele  ade1 mutant allele  5’...TTATGGGCAAGATCCCA...3’  5’....TTA TGGGCTAGATCCCA...3’  3’...AATACCCGTTCTAGGGT...5’  3’...AATATGGGCTAGATCCCA...3’ \begin{array} { c c } \text { ade } 1 ^ { + } \text {wild-type allele } & \text { ade1 } ^ { - } \text {mutant allele } \\\text { 5'...TTATGGGCAAGATCCCA...3' } & \text { 5'....TTA TGGGCTAGATCCCA...3' } \\\text { 3'...AATACCCGTTCTAGGGT...5' } & \text { 3'...AATATGGGCTAGATCCCA...3' }\end{array}
-How does the mutation affect the enzyme?


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