Which of the Following Statements Explaining the Mechanism of Action

question 59

Multiple Choice

Which of the following statements explaining the mechanism of action of telomerase is correct? (Select all that apply.)

• A) The extension of telomeres via telomerase occurs at the 3ʹ overhang with a G-rich sequence.
• B) Telomerase carries a short single-stranded DNA component that is used as a template to extend the telomere.
• C) The extension of telomeres via telomerase occurs at the 5ʹ end, where DNA polymerase cannot add a new deoxynucldotide after the removal of the very last RNA primer.
• D) The extension at the 3ʹ overhang is followed by the extension of 5ʹ complementary strand via a currently unknown mechanism.
• E) Telomerase finishes complementary base pairing of the 5ʹ complementary strand.

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Definitions:

LH

Luteinizing Hormone, a hormone produced by the anterior pituitary gland that triggers ovulation and stimulates the production of estrogen and progesterone in females, and testosterone in males.

FSH

A gonadotropin, a glycoprotein polypeptide hormone synthesized and secreted by the pituitary gland which regulates the development, growth, pubertal maturation, and reproductive processes of the body.

Estrogen

A group of steroid hormones that play an important role in the regulation of female reproductive cycles and secondary sexual characteristics.

Temporary Endocrine Gland

A gland that appears only during certain periods of life and secretes hormones, such as the corpus luteum in females.