Which of the Following Would Be Most Useful in a Synthetic

question 1

Multiple Choice

Which of the following would be most useful in a synthetic circuit to accelerate a screen for drugs that inhibit the activity of a negative transcription regulator,EthR,from Mycobacterium tuberculosis?

• A) translational fusion of VP16 with a reporter gene
• B) translational fusion of ethR with the VP16 transcriptional activator
• C) translational fusion of ethR with a reporter gene
• D) place VP16 under control of the cis-element to which EthR native binds promoter
• E) place GFP under control of the cis-element to which EthR native binds promoter

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Definitions:

Trachea

The windpipe, a large tube that connects the larynx to the bronchi of the lungs, allowing for air passage.

Villi

Small finger-like projections that protrude from the epithelial lining of the intestinal wall, increasing surface area for nutrient absorption.

Fingerlike Projections

Extensions from a surface or body that resemble fingers, often used to increase surface area for absorption or sensation in biological systems.

Mucosa

The moist, inner lining of some organs and body cavities, such as the nose, mouth, lungs, and stomach.